微纳电子技术

基于行波介电泳原理,分析了电场强度和Clausius-Mossoti(C-M)因子的虚部对行波介电泳力的影响。对4种不同形状电极的电场强度分布进行了仿真建模,结果表明半圆形电极阵列有较好的传输特性,并建立了半圆形电极阵列在行波作用下的电场模型。以行波介电泳力的复数表达式为基础,得出了C-M因子虚部随频率的变化曲线。设计加工了基于半圆形电极阵列的细胞分离微流体芯片,基于行波介电泳原理,对金黄色葡萄球菌细菌进行了分离实验。通过对比分析,实验结果与仿真结果具有较好的一致性。因此,利用行波介电泳力,半圆形电极阵列能够有效地对细菌进行传输分离。

The effects of the electric field strength and the imaginary part of Clausius-Mossoti(C-M)factor on the travelling-wave dielectrophoresis force were analyzed based on the principle of the travelling-wave dielectrophoresis.The electric field strength distributions for the electrodes with four different shapes were simulated and modeled.The results show that the semicircle electrodes array has better transmission performances.The electric filed model of the semicircle electrodes array was built under the effect of the travelling-wave.According to the plural expressions of the travelling-wave dielectrophoresis force,the change curve of the imaginary part of C-M factor with the frequency was obtained.The microfluidic chip for cell separation was designed and fabricated based on the semicircle electrode array.Based on the theory of travelling-wave dielectrophoresis,the separation experiment of staphylococcus aureus was carried out.The experiment results are well consistent with the simulation results through the comparative analysis.Therefore,the semicircle electrode array can efficiently transport and separate the bacteria by using the travelling-wave dielectrophoresis force.